| abstract |
An isolated Toll-like-receptor polypeptide comprises the amino acid sequence of SEQ ID NO: 2, a variant or a fragment thereof which has immunomodulatory activity. Polynucleotides encoding such a Toll-like receptor are also described. A method for identification of a substance that modulates Toll-like receptor activity comprises contacting a polypeptide of the invention with a test substance and monitoring for immunomodulatory activity. |