| abstract |
Compounds represented the general formula (I) exhibit affinities for various serotonin receptors (such as 5HT-1A, 2, 6, 7, and so on) and are therefore useful as remedies for central nervous system diseases or the like wherein R?1 and R2¿ are each independently hydrogen, lower alkyl, or the like; R?3 and R4¿ are each independently hydrogen, lower alkyl, or the like; or alternatively R?1 and R3¿ may be united to form a single bond; n is 0 or 1; R5 is hydrogen; R6 is hydrogen, hydroxyl, or the like; R7 is hydrogen; R?8 and R9¿ are each independently hydrogen, lower alkylthio, or the like; or alternatively R?7 and R9¿ may be united to form a single bond; R10 is hydrogen, lower alkyl, or the like; R11 is hydrogen, lower alkyl, or the like; and R12 is hydrogen or lower alkyl |