abstract |
Having an affinity against serotonine receptors, compound (I) shownnbelow is useful as a therapeutic agent against various kinds of diseases ofncentral nervous systems.n n(wherein R 1 is hydrogen ; R 2 is hydrogen or lower alkyl ; R 3 is hydrogen,-COOR 12 nand so on ; R 4 is hydrogen, lower alkyl and so on, or R 3 and R 4 takenntogether may form =O or =S; R 5 is hydrogen, or R 3 and R 5 taken together maynform a bond ; R 6 is hydrogen, -COOR 24 and so on ; R 7 is hydrogen, halogen,nlower alkyl and so on ; R 8 is hydrogen, lower alkyl, cycloalkyl and so on ; R 9 ,nR 10 and R 11 are each independently hydrogen, halogen, lower alkyl and so on) |