| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c198757da18cf77dfbdcef00abb70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f137c31e20b6212272dde0619058fce3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e300c05e5439225bd3d75c9d23ef |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate |
2000-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24c7806d9108604680467fe457a56c62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a71e5a7a2be086291f6a924e3ef90f1 |
| publicationDate |
2000-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0055133-A1 |
| titleOfInvention |
1-acyl-7-nitroindoline derivatives, their preparation and their use as photocleavable precursors |
| abstract |
Photoreleasable compounds comprising a caging moiety linked to an effector moiety represented by structural formula (I) wherein R1 is hydrogen; C1-10 alkyl or substituted alkyl; O(CH2)n-Y; N(COZ)(CH2)mY; or N[(CH2)mY'[(CH2)NY]; R2 and R3 are independently selected from: hydrogen; C1-10 alkyl or substituted alkyl; or R2 and R3 together are cycloalkyl; R4 is hydrogen; C1-10 alkyl or substituted alkyl; phenyl or substituted phenyl; (CH2)nY; or (CH2)mO(CH2)nY; wherein m and n are independently between 1 and 10; Y and Y' are independently selected from hydrogen, CO2H or salts thereof or OPO32-; Z is hydrogen or C¿1-10? alkyl or substituted alkyl; and, X is an effector moiety or a group capable of being coupled or converted to an effector moiety, which are capable of releasing the effector moiety on irradiation, typically by flash irradiation with UV light. The photoreleasable compounds can therefore be used to deliver biologically active effector moieties such as neuroactive amino acids or metal chelators to sites where their activity is required. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112479971-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013050795-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1757585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11370757-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112479971-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013050798-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9650664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02083639-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004085394-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104011020-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7737169-B2 |
| priorityDate |
1999-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |