| abstract |
A method for purifying a sugar polyol product stream is provided by the invention. The process facilitates the isolation and recovery of sugar polyol from a culture generated by polyol-producing microorganisms. The method employs a pretreatment operation which includes microbial cell separation in combination with the removal and/or deactivation of proteinaceous material. In one embodiment of the method, microbial cells are separated from the fermentation broth without disruption of the cells, thereby avoiding the release of substantial amounts of intracellular components, cell organelles and related components into the culture broth. |