Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd349720591ada70f787e80bb5b6e415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d5592e9db177d1b7365a350d9208f34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64f32be5e3d2414cd9eba2ca3ba9c5ee |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209374e1e16789decb55247399d4fcd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc0ed151d6c31a503b5482d3ecf250e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e796bd684971c0ed9cf10bc37ae2fab6 |
publicationDate |
2000-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0015209-A2 |
titleOfInvention |
REGULATION OF HER2/neu ONCONGENE EXPRESSION BY SYNTHETIC POLYAMIDES |
abstract |
Methods and compositions comprising polyamides capable of binding the minor groove of double-stranded DNA are described for the inhibition or reduction of gene transcription and expression. The polyamides comprise at least four complementary pairs of aromatic carboxamide residues which are selected to specifically contact and/or bind to the nucleotide sequence of a double-stranded DNA target in the promoter region of the target gene. The methods, compositions and polyamides are disclosed for the inhibition of oncogene transcription and expression as well as the treatment of cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7122626-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7129214-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6716866-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7498405-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7030099-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7642245-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7498349-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6777425-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7348427-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7329765-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7265129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6825228-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0210368-A1 |
priorityDate |
1998-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |