Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f01d5abd5a8ae2402e2a04642e535923 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 |
filingDate |
2013-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_477870f386b649676f96c0fff8dbdcd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef1023e4ac8c092987c00835446e58fa |
publicationDate |
2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9890213-B2 |
titleOfInvention |
Methods for the treatment of B cell-mediated inflammatory diseases |
abstract |
Methods for treating diseases associated with chemokine (C-X-C motif) ligand 13 (CXCL13) expression, including certain autoimmune and inflammatory diseases such as Sjogren's syndrome are provided herein. The methods comprise administering to a subject in need thereof an effective amount of an agent that inhibits CXCL13 activity. According to aspects of the invention illustrated herein, there is provided a method of treating, preventing, or reducing the exacerbation of a B-cell-mediated inflammatory condition in a subject, including administering to a subject an effective amount of an isolated binding molecule which specifically binds to CXCL13, wherein said molecule prevents or inhibits CXCL13 activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640765-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11078295-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662422-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10550199-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10577427-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11534488-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526414-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11274149-B2 |
priorityDate |
2012-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |