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filingDate 2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9840742-B2
titleOfInvention Detection of hepatitis B virus (HBV) DNA and methylated HBV DNA in urine of patients with HBV-associated hepatocellular carcinoma
abstract This application relates to a DNA marker for HBV-HCC detection and the methods, kits for quantitatively measuring the amount of HBV DNA and bisulfite treated HBV DNA, and methylated HBV DNA, and the aberrant methylation of the HBV genome for the used in the chronic HBV infected populations. Detection of the presence or absence of HCC, with elevated methylation levels in the one or more regions of DNA of the mammals as compared to the level of methylation in the one or more regions of DNA in the one or more control body fluids or tissues indicating the presence of the cancer, and the absence of elevated methylation levels indicating the absence of HCC.
priorityDate 2014-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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