| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f35c1a935a6193e6ebabbac1340a0aa5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be4412d8bb16f4614e79cd4b6000cc34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac76eb8c83729f28fa623843708ebba4 |
| publicationDate |
2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011256538-A1 |
| titleOfInvention |
Epigenomic dna modifications for tissue typing, early cancer detection, and disease management |
| abstract |
Provided herein is a suitable method for detecting the presence or absence of a cancer in an individual, by determining the level of methylation of the sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of detecting the presence or absence a cancer in an individual by determining if there is an apparent 100% methylation by assay of the CpG sites in the anti-sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of tissue typing by determining the level of methylation of the anti-sense strand of a selected regulatory region of a tumor suppressor gene indicating an enhanced likelihood that a tissue is liver. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109790198-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10197565-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9840742-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11243200-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018045322-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3507298-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015361505-A1 |
| priorityDate |
2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |