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publicationDate 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9766247-B2
titleOfInvention Rapid method to analyze ubiquitin-proteasome activity and to screen for ubiquitin-proteasome inhibitor
abstract Provided are a method of analyzing ubiquitin-proteasome activity with respect to a target polypeptide and a method of screening a ubiquitin-proteasome inhibitor. According to the provided methods, the pattern of lysis of a target polypeptide by a ubiquitin-proteasome in target cells may be quantitatively analyzed in a rapid and highly sensitive way, a ubiquitin-proteasome inhibitor may be screened in a rapid and highly sensitive way, and an anticancer agent and the activity thereof may be rapidly screened.
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