Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-60 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-60 |
filingDate |
2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3927d006f413ac30a8a8678a305d6482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff6894ee7057b5d5cb475ca8e09d170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b788ae1ec1e676c2adde066b43c4fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adc2a9fef889b9adccb699bee7c450c4 |
publicationDate |
2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9725425-B1 |
titleOfInvention |
Compounds and methods for treating cancer |
abstract |
Provided are small molecule inhibitors of ubiquitin specific protease 2, 8 and 12 (USP2 and USP8 and USP12) activity and methods for their use in treating cancers. The small molecule inhibitors of the invention are particularly useful in the treatment of non-small cell lung cancers that are resistant to tyrosine kinase inhibitors and in the treatment of prostate cancer that is resistant to AR inhibitor therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10653676-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450281-B1 |
priorityDate |
2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |