Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0597f9c318d2aeca86db94711c516383 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1d32ba26b217f77cf7b1b0a65cc0d77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7793940bc171b97e2de6279e8c1b53e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb4d0faa660c771f63d0f516e210d38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b808184e4b68747c76dd9badb8ef4089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d48f321435b52d967864cb19c3171987 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ead9f125f35b9128d40e368c5404d112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4647092e9c87a91e9ddffa311f0c3c54 |
publicationDate |
2017-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9636418-B2 |
titleOfInvention |
Potent and selective inhibitors of NAV1.7 |
abstract |
Disclosed is a composition of matter comprising an isolated polypeptide, which is a peripherally-restricted Na V 1.7 inhibitor. In some disclosed embodiments, the isolated polypeptide is an inhibitor of Na V 1.7. Other embodiments are conjugated embodiments of the inventive composition of matter and pharmaceutical compositions containing the inventive composition of matter. Isolated nucleic acids encoding some embodiments of inventive polypeptides and expression vectors, and recombinant host cells containing them are disclosed. A method of treating or preventing pain is also disclosed. |
priorityDate |
2013-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |