http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9498320-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dfd32233aea2ab1d0d6a964cbda5c00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cc42502140cfb0b2ff524e6becc8074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d938aa1b75b88f5a116a30536dc97b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a7ebd2ce5ef7e691bd44c48a88a2bfc |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-068 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 |
filingDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9381e841d06ea3317d81fe6e50fc6df6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4a9961a51dbc1a2d6dccae25a7b4c6f |
publicationDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9498320-B2 |
titleOfInvention | Biomimetic vascular network and devices using the same |
abstract | The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e). The invention also provides compositions comprising a vascular layer for use in tissue lamina as well as a medical devices having a vascular layer and kits. |
priorityDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.