| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b365ecd292347f6360d28f9f364beeef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d5f75491f6070c9fcc717157fb5ef0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dfd32233aea2ab1d0d6a964cbda5c00 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-068 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-062 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 |
| filingDate |
2010-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dc6c154882876d261ad76694a60b344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19f71db0e180020e63518811b8d7b8d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80aa9108aad5038d2712bb3f8b47257b |
| publicationDate |
2013-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8591597-B2 |
| titleOfInvention |
Biomimetic vascular network and devices using the same |
| abstract |
The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e). The invention also provides compositions comprising a vascular layer for use in tissue lamina as well as a medical devices having a vascular layer and kits. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9498320-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014087454-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014081384-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D851276-S
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013236503-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9861663-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8735143-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11534530-B2 |
| priorityDate |
2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |