http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9302987-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 |
filingDate | 2015-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c0b6b7b01e10821994f74279d248522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5443fd31846ad15181c7bd6bc573305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76510c15a5e52be1db3f6c70ea52216d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb279e9e6f3b27206cdfcb8b9380f5bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b8016ab1f2fa4bddd6798741347ea8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2610f53f3758d6d739d69c805b3852 |
publicationDate | 2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9302987-B2 |
titleOfInvention | Pyrrolidinyl derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
abstract | The N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, whereinn n is 1 or 2; L represents a C 1-3 alkyl linker optionally substituted with one or two substituents selected from C 1-4 alkyl, C 1-3 alkyloxy-C 1-4 alkyl-, hydroxy-C 1-4 alkyl, hydroxy, C 1-3 alkyloxy- or phenyl-C 1-4 alkyl; M represents a direct bond or a C 1-3 alkyl linker optionally substituted with one or two substituents selected from hydroxy, C 1-4 alkyl or C 1-4 alkyloxy; R 1 and R 2 each independently represent hydrogen, halo, cyano, hydroxy, C 1-4 alkyl optionally substituted with halo, C 1-4 alkyloxy- optionally substituted with one or where possible two or three substituents selected from hydroxy, Ar 1 and halo; or R 1 and R 2 taken together with the phenyl ring to which they are attached form naphtyl or 1,3-benzodioxolyl, wherein said naphtyl or 1,3-benzodioxolyl are optionally substituted with halo; R 3 represents hydrogen, halo, C 1-4 alkyl, C 1-4 alkyloxy-, cyano or hydroxy; R 4 represents hydrogen, halo, C 1-4 alkyl, C 1-4 alkyloxy-, cyano or hydroxy; R 5 represents hydrogen, C 1-4 alkyl or Ar 2 —C 1-4 alkyl-; R 6 represents hydrogen, halo, C 1-4 alkyl or C 1-4 alkyloxy-; Ar 1 and Ar 2 each independently represent phenyl or naphtyl wherein said phenyl and naphtyl are optionally substituted with C 1-4 alkyl, C 1-4 alkyloxy-, or phenyl-C 1-4 alkyl;n nfor use as a medicine. |
priorityDate | 2004-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 841.