abstract |
ABSTRACT Phenol derivatives of use in promoting formation of nerve growth factor are of the general formula (Ia) or (Ib) (Ia) (Ib) (wherein, each R1 is hydrogen or a hydroxy-protecting group; either R2 is alkyl, cycloalkyl, cycloalkyl condensed with aryl, aryl, aralkyl or heterocyclic; and R3 is hydrogen or a group R2; or R2 and R3, with the nitrogen atom to which they are attached, represent a cyclic amino group; m is 1 to 6; n is 1 to 3, provided that when n is 2 or 3 then two adjacent groups R1 may jointly form a hydroxy-protecting group; p is 0 or 1 to 3; q is 0 or 1 to 3; and the bond marked with a dashed line may be a single bond or a double bond); or a pharmaceutically acceptable salt thereof. |