http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273022-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fb321232bee0732c6df620418bedb0c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-82 |
| filingDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cbae2390e39d9d0cdd3098f5e2131dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f7074fcbe4c5db804bd26c76b8b3e32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d3f6be41cb2186a941d672cc5f3a55c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd33b4f8c737e66f1d17d284cbbe9cd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f1cc813b6d52e906619b4ebc6c3aa2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bf9b63dcfc90d9422cf226392716746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b268ee09feb20eb79455850c76e57703 |
| publicationDate | 2016-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9273022-B2 |
| titleOfInvention | Process for the synthesis of 4,5,6,7-tetrachloro-3′,6′-dihydroxy-2′, 4′, 5′7′-tetraiodo-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (Rose Bengal) and related xanthenes |
| abstract | A new process for the manufacture of iodinated xanthenes in high purity includes a cyclization step followed by an iodination step. No extraction, chromatographic or solvent concentration steps are required, and the intermediate as well as final compounds are isolated via filtration or similar means. The process requires a single organic solvent, and the steps are completed at temperatures below 100° C. The exclusion of chloride ions, of chloride free-radicals, hypochlorite ions, or hypochlorous acid as reagents or from reagents that may generate these species in situ in the presence of oxidants, prevents undesirable impurity formation. Several new compounds have been conceived and isolated using these methods. These new compounds are also formed into new medicaments. |
| priorityDate | 2009-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 219.