| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee6b113b79349a731bce050dff0b2031 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-78 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-78 |
| filingDate |
2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_333ad5290489082577266b3ddca73ed5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c06d86749989d3f48e0283f0ff4aa335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_695ed888d76ab557ade9a4f0692f0d95 |
| publicationDate |
2015-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9109229-B2 |
| titleOfInvention |
Process for improved protein expression by strain engineering |
| abstract |
This invention is a process for improving the production levels of recombinant proteins or peptides or improving the level of active recombinant proteins or peptides expressed in host cells. The invention is a process of comparing two genetic profiles of a cell that expresses a recombinant protein and modifying the cell to change the expression of a gene product that is upregulated in response to the recombinant protein expression. The process can improve protein production or can improve protein quality, for example, by increasing solubility of a recombinant protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9878023-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541105-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10041102-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10689640-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394571-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10954521-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020237246-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10857233-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580719-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9458487-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9737592-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11219671-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486513-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828350-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10364435-B1 |
| priorityDate |
2004-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |