| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48ee639efc2a1236f389cb9f6cf614d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93e6b1a2e05af87990a81206264acff1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-44 |
| filingDate |
2013-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_642390f282199259e3f812eb2839310c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8814b5a85bc10cb8748aed6ade4d918a |
| publicationDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9012645-B2 |
| titleOfInvention |
Process for the preparation of 6-(7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide and synthetic intermediates thereof |
| abstract |
A process for the preparation in high yields and purity of the compound 6-(7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide of formula (I) and of the pharmaceutically acceptable salts thereof is described. The process has various advantages over those previously described, in particular it avoids the use of acyl azide intermediates and their Curtius rearrangement. Novel intermediates useful for the preparation of compound (I) are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9340508-B2 |
| priorityDate |
2009-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |