| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e843d3e1376c697b8327b19725622a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb81152625d9dd5720395d3b1a91700f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1327e82773a11b9fa348df607135aaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_362d7df142655613551c77e74b6366de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_991b0ddbfcbca94f2733f8aff3ad0b58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25f874910e49bb676c35c675f91ece39 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 |
| filingDate |
2011-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_592ca9691558fd1a22c7f22e94c27620
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b065f4c8868758bdb77189f72fae349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_304de120b32259b538b3439551fb6f8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98390418ec86d07ec32f8707ed7e454b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b4be00609a60469d7fe9142de097536 |
| publicationDate |
2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8921596-B2 |
| titleOfInvention |
Process for the preparation of melphalan hydrochloride |
| abstract |
The present invention provides a simple and efficient method for synthesis of 4-[bis(2-chloroethyl)-amino]-L-phenylalanine hydrochloride. The process involves the treatment of 4-[bis(2-chloroethyl)-amino]-L-phenylalanine free base with hydrochloric acid in water followed by isolation of 4-[bis(2-chloroethyl)-amino]-L-phenylalanine hydrochloride of desired purity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019037591-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109422660-A |
| priorityDate |
2010-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |