| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64b639e071afa15ff59264c89c1657c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202bc6707721996be5668bab701f341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9855f853f24337072ce02f44383942c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b65624ee4f8c8878257c719b891719b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B10-0041 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2012-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e17a1c49eec596d8597f94f3cb3426d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dbf9955063e6b1262ed5879d3328f5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2df7767de2eebe9a655e4044c73e6cd |
| publicationDate |
2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8914238-B2 |
| titleOfInvention |
Method for predicting breast cancer patient response to endocrine therapy |
| abstract |
A mass-spectral method is disclosed for determining whether a breast cancer patient is likely to benefit from administration of a combination treatment in the form of a targeted anti-cancer drug in addition to an endocrine therapy drug. The method obtains a mass spectrum from a blood-based sample from the patient. The spectrum is subject to one or more predefined pre-processing steps. Values of selected features in the spectrum at one or more predefined m/z ranges are obtained. The values are used in a classification algorithm using a training set comprising class-labeled spectra a class label for the sample is obtained. If the class label is “Poor”, the patient is identified as being likely to benefit from the combination treatment. In a variation, the “Poor” class label predicts whether the patient is unlikely to benefit from endocrine therapy drugs alone, regardless of the patient's HER2 status. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3779998-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11710539-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685954-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018013466-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10950348-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017011439-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11150238-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019118873-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10007766-B2 |
| priorityDate |
2011-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |