Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9855f853f24337072ce02f44383942c9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-40 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-10 |
filingDate |
2011-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d56de4022aea44bf70fcb6c455aa7f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5080ba90e79bdf07cdf32457639384d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0066944fab2e4cc56ce9138ae1b722e7 |
publicationDate |
2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011208433-A1 |
titleOfInvention |
Cancer patient selection for administration of therapeutic agents using mass spectral analysis of blood-based samples |
abstract |
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a solid epithelial tumor cancer patient is likely to benefit from a therapeutic agent or a combination of therapeutic agents targeting agonists of the receptors, receptors or proteins involved in MAPK (mitogen-activated protein kinase) pathways or the PKC (protein kinase C) pathway upstream from or at Akt or ERK/JNK/p38 or PKC, such as therapeutic agents targeting EGFR and/or HER2. The methods also provide the ability to determine whether the cancer patient is likely to benefit from the combination of a therapeutic agent targeting EFGR and a therapeutic agent targeting COX2; or whether the cancer patient is likely to benefit from the treatment with an NF-κB inhibitor. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150023881-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015157109-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10593529-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019118873-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9653272-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11152197-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11594403-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10837970-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104685360-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10217620-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11624750-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014003853-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8914238-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8718996-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9606101-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014007859-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013281221-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11710539-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021118538-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016379811-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10950348-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10037874-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015528110-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11150238-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10007766-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017011439-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102103319-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9254120-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3779998-A1 |
priorityDate |
2010-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |