Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee6ed950166e85c93655f5470be6dd30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fec97fb88a24b5db196778d1c3808e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d47a26c0ba2a3a191b0e38665b71d95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_242dd748d1d8a2b1ab587dd5fdebee7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b72d21a9580a829931009549e33f0b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f300655afea494baff2c3e0e312f29 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
filingDate |
2012-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ffc678193afc85f200ee0eb6a520b71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf9a4161355814798d582a73c5e472d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c03c88e5f20f6f302a94a3f27d49fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98a644b80e6bb1ffb03384bf43f66a16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9426fab15ca1acf2efa4b0b9eedc787d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_434d35dfd9223c5643218235519d4d1e |
publicationDate |
2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8859493-B2 |
titleOfInvention |
Insulin derivatives |
abstract |
The present invention is related to insulin derivatives having a side chain attached either to the α-amino group of the N-terminal amino acid residue of B chain or to an ε-amino group of a Lys residue present in the B chain of the parent insulin molecule via an amide bond which side chain comprises one or more residues of ethyleneglycol, propyleneglycol and/or butyleneglycol containing independently at each termini a group selected from —NH 2 and —COOH; a fatty diacid moiety with 4 to 22 carbon atoms, at least one free carboxylic acid group or a group which is negatively charged at neutral pH; and possible linkers which link the individual components in the side chain together via amide or ether bonds, said linkers optionally comprising a free carboxylic acid group. |
priorityDate |
2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |