Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1d52f0c4cf6cced0cc643f5614fe892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff0605642137c8b3bdf24fe9534a67a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53a4bb70199bb7d253741474559f4431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58fc6aba01b821a887376ba47f60a16b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1276 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2010-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd5d945472518fdf7570730c0dc842f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b552e5612a7c30536ef6795058b662b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f1d4fc196a4f4d05180027dde6ac46c |
publicationDate |
2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8835148-B2 |
titleOfInvention |
Production of nucleic acid |
abstract |
The present invention provides a process for the production of nucleic acid encoding a target protein, which comprises: (a) providing an array of RNA or DNA molecules including one or more encoding the target protein; (b) generating a target protein from the array to form RNA-protein or DNA-protein complexes in which the RNA or DNA molecule is non-covalently or covalently bound to the complex; (c) separating the complexes into compartments wherein most or all of the compartments contain no more than one complex; (d) subjecting the complexes to reaction conditions which allow target protein activity; and (e) selecting nucleic acid encoding the target protein on the basis of the activity associated therewith, wherein when the complex is a DNA-protein complex in which the DNA is non-covalently bound, step b) is performed in the absence of separate compartments for each complex. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9771565-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011081704-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9663770-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10358670-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932567-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021115415-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862938-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019122200-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2023090221-A1 |
priorityDate |
2008-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |