| abstract |
A diazepinedione derivative represented by the formula (I) or a pharmacologically acceptable salt thereof is used as a P2X 4 receptor antagonist: n nwherein R 1 represents a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, or the like, R 2 and R 3 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a halogen atom, or the like, R 4 and R 5 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, or the like, and W represents tetrazole or the like. |