| abstract |
The present invention relates to a screening method for a compound useful for treatment of neuropathic pain, and therapy for the treatment of neuropathic pain. The screening method comprises determining inhibitory activity on the action of P2X 4 receptor or inhibitory activity on the activation of microglia, of test compounds. The pharmaceutical composition and the therapy employ a P2X 4 receptor inhibitor or a microglial activation-inhibitor as active ingredient. |