http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8778610-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9c85f88a68ac6ee5a3d44d5b6cd881b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6846 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cafbbe173d12d94497f94900b35dc083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73f3be9acc123427d1080f35f05137a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b44793d7db49617992f86ba902436ba9 |
| publicationDate | 2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8778610-B2 |
| titleOfInvention | Methods for preparing amplifiable DNA molecules |
| abstract | The present invention concerns isolation, library preparation and selective amplification from a compositionally heterogeneous pool of DNA fragments of a fraction of molecules, such as those originating from promoter CpG islands and characterized by a high GC content. In particular, the process utilizes a heat-induced segregation of DNA molecules into GC-poor, single-stranded molecule fractions and GC-rich, double-stranded molecule fractions, with subsequent enzymatic conversion of the GC-rich, double-stranded DNA molecules into a library, and, optionally, amplification. In specific embodiments, the isolation process is used to generate promoter-enriched genomic and methylome libraries for research and diagnostic applications, for example. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10155942-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961529-B2 |
| priorityDate | 2005-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.