| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23a4e0c875bf1ac2b8a3b76517de6c7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ed1467b45cd944a9ab06e40e0c8c85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea77a342998d21e24b3d64e809a59570
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2117d0d5a1f84b2285a00d7451ce8874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88705bdd8265a03595316d09782bc73e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C28-345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C28-322 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C25B11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate |
2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_817fdedab94a116f039429192186f08e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09fac4e3f1ead06d82e42811ca516a80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d89d904a1e4da8d4107b74ef1c367c48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d619fb6c2f6224984733126cddb8f3c6 |
| publicationDate |
2014-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8715981-B2 |
| titleOfInvention |
Electrochemical biosensor |
| abstract |
Networks of single-walled carbon nanotubes (SWCNTs) decorated with Au-coated Pd (Au/Pd) nanocubes are employed as electrochemical biosensors that exhibit excellent sensitivity (2.6 mA mM −1 cm −2 ) and a low estimated detection limit (2.3 nM) at a signal-to-noise ratio of 3 (S/N=3) in the amperometric sensing of hydrogen peroxide. Biofunctionalization of the Au/Pd nanocube-SWCNT biosensor is demonstrated with the selective immobilization of fluorescently labeled streptavidin on the nanocube surfaces via thiol linking. Similarly, glucose oxidase (GOx) is linked to the surface of the nanocubes for amperometric glucose sensing. The exhibited glucose detection limit of 1.3_M (S/N=3) and linear range spanning from 10 μM to 50 mM substantially surpass other CNT-based biosensors. These results, combined with the structure's compatibility with a wide range of biofunctionalization procedures, would make the nanocube-SWCNT biosensor exceptionally useful for glucose detection in diabetic patients and well suited for a wide range of amperometric detection schemes for biomarkers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11592414-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016205558-A1 |
| priorityDate |
2009-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |