| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_726204a0917d52d04d7251c22b5c5121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B35-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B35-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06G7-56 |
| filingDate |
2001-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b01526f61f0fe856a4d3767c502964ec |
| publicationDate |
2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8606553-B2 |
| titleOfInvention |
Methods for identifying drug targets based on genomic sequence data |
| abstract |
This invention provides a computational approach to identifying potential antibacterial drug targets based on a genome sequence and its annotation. Starting from a fully sequenced genome, open reading frame assignments are made which determine the metabolic genotype for the organism. The metabolic genotype, and more specifically its stoichiometric matrix, are analyzed using flux balance analysis to assess the effects of genetic deletions on the fitness of the organism and its ability to produce essential biomolecules required for growth. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188722-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015112652-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10480375-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1 |
| priorityDate |
1999-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |