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filingDate 2009-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8597889-B2
titleOfInvention Method for detecting cancer cell caused by HPV, method for determining whether or not tissue is at stage of high-grade dysplasia or more severe stage, and primer set and kit used therefor
abstract Provided are a primer set, a method and a kit therefor, which can easily perform with high accuracy the detection of a cancer cell caused by HPV and the determination of whether or not a tissue is a tissue with high-grade dysplasia or in a more severe phase. As a primer set, used is a primer set consisting of a first primer which hybridizes with a nucleic acid consisting of a nucleotide sequence in which cytosine present in a site other than a CpG site is converted into another base in a nucleotide sequence having a CpG site in L1 region or L2 region of HPV and a second primer which hybridizes with a nucleic acid consisting of a nucleotide sequence in which cytosine is converted into another base in a nucleotide sequence having a CpG site in LCR or E6 region of HPV.
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