Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd3e72a2b5e4b283bf2d78febf0b7185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e990db2f0579f7e574aa9a8f14e7d553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_612e18032d76efefa09f78ec39692116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05df0446a200da441dfc383c3f3a5c37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7785c9b9aa3041447680aaab1ece2bfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb6274683d33d7bd9aebc454358e3963 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
2005-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b32c23d58bbaf0d7f4dfd7876938a32a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a70b34bdd8c5ff8d9f46bef48915e994 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79cb869a0da350a1aa218f2a5d4386c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8c04b2f180a6c8392ae08ee87572abb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6414549fd931e5e638ddcd756b7db6bf |
publicationDate |
2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8445664-B2 |
titleOfInvention |
Kits for amplifying and detecting nucleic acid sequences |
abstract |
This invention provides novel processes for amplifying nucleic acid sequences of interest, including linear and non-linear amplification. In linear amplification, a single initial primer or nucleic acid construct is utilized to carry out the amplification process. In non-linear amplification, a first initial primer or nucleic acid construct is employed with a subsequent initial primer or nucleic acid construct. In other non-linear amplification processes provided by this invention, a first initial primer or nucleic acid construct is deployed with a second initial primer or nucleic acid construct to amplify the specific nucleic acid sequence of interest and its complement that are provided. A singular primer or a singular nucleic acid construct capable of non-linear amplification can also be used to carry out non-linear amplification in accordance with this invention. Post-termination labeling process for nucleic acid sequencing is also disclosed in this invention that is based upon the detection of tagged molecules that are covalently bound to chemically reactive groups provided for chain terminators. A process for producing nucleic acid sequences having decreased thermodynamic stability to complementary sequences is also provided and achieved by this invention. Unique nucleic acid polymers are also disclosed and provided in addition to other novel compositions, kits and the like. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10745745-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10017809-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10131939-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015187849-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450595-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10093918-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9416387-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10522245-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10283217-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9725760-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603558-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11649487-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9551027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254960-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9916428-B2 |
priorityDate |
1998-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |