| abstract |
Disclosed are compounds of Formula (I) n nor a stereoisomer or a pharmaceutically acceptable salt thereof, wherein:n A is nn n n n n n n n n n Q is a substituted 5-membered monocyclic heteroaryl group; n W is CH 2 , O, or NH; and R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P 1 , and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease. |