| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edca6dde4afe3ac1c2471819bfd0117a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c6c8469ba04ffba75674344a19b6517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_017a86afceac39dc24934c3d7cced525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a30d4441c24876141f2a07b6efff8b6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0515670cbec9e347be1cbfa61b2e22a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcf6c7042b3ac329c3f5153104c3b1c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efad2bbe52af7a8ebd7bc8cb7fbfcc4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_975a85aa4e84660affdde8ec36e44959 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64a37e1c1815c32d2f9b97d9cc390c5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1b809be2928c73df6e2dc073b130a1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_033e795dcf0ba5639f5cbd3dd266f3bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af5d1776fdc7665d6537ae62d22fb53d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04c2b273d90f2db8ca073a2fb252d41b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf4efbe6be5e2925822f13ce8b6193f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54ef6614289b34922265a036b7634f9b |
| publicationDate |
2012-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8314075-B2 |
| titleOfInvention |
Compositions and methods for inhibiting expression of huntingtin gene |
| abstract |
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Huntingtin gene (HD gene), comprising an antisense strand having a nucleotide sequence which is less than 25 nucleotides in length and which is substantially complementary to at least a part of the HD gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the HD gene, or a mutant form thereof, using the pharmaceutical composition; and methods for inhibiting the expression of the huntingtin gene in a cell. |
| priorityDate |
2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |