| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25935c610a3c0c769e6680483531dc6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3662ce5995dada5ea3d9873552592af0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2ecd9ea24dae4cfdf98a7928666c469
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a6153675df7dec3579f09daa6619237
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df718b1fa60c08eee03f98a875b78c3c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-868
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-862
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-805 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4291
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21dde8c8524a11b2b5cfa06184039622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95ae6c10d681bb7bd67bbe1f90ae869a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e945ee9a60a387d03651f3ca97df425b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c36f6b3ae3f5eb41c00916d49832f85b |
| publicationDate |
2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8137670-B2 |
| titleOfInvention |
Method of identifying membrane IgE specific antibodies and use thereof for targeting IgE producing precursor cells |
| abstract |
The present invention relates to the discovery of antibodies that bind to novel epitopes present on membrane-anchored IgE and which bind to these novel epitopes on the surface of B cells and plasma cells. In addition, the antibodies of the present invention can mediate ADCC and can be useful to deplete those B cells and plasma cells expressing the novel epitopes of the invention. The antibodies of the present invention can be useful for the treatment of IgE-mediated diseases. Accordingly the present invention also provides compositions and methods for the prevention, management, treatment or amelioration of IgE-mediated diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012207746-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8741294-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8460664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013158274-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9587034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8974794-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11439682-B2 |
| priorityDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |