| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff987fcc98c2a781f82b2f2165f478e4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-402 |
| filingDate |
2007-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b57f676cec41c6159468ac1afa7d3c80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b230b1c7085b8ea455aac454d31b326 |
| publicationDate |
2011-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8048908-B2 |
| titleOfInvention |
11β-hydroxysteroid dehydrogenase type 1 active compounds |
| abstract |
The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions, are described. Also a novel class of substituted amides, of the general formula I. Their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds are modulators and more specifically inhibitors of the activity of 11βHSDI and may be useful in the treatment of a range of medical disorders where a decreased intracellular concentration of active glucocorticoid is desirable. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020102314-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011224244-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8513430-B2 |
| priorityDate |
2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |