Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85b959d2100bb308fcf773d125a37ab8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-76 |
filingDate |
2006-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_386110e025ceb2cbcecd220a20fb2c29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_580ba9a12c3db74ce141ccdf99a4253a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7a6d02bc08a9fb0b72fb642c1eda06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f2fc28fc514ee0fbde3c74595254a56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852bbfbe2f76870fa0915df27ecc770d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd0880b2b89921ac1f1afb89e791b829 |
publicationDate |
2011-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7981635-B2 |
titleOfInvention |
Cleavage of precursors of insulins by a variant of trypsin |
abstract |
The present invention relates to the production of a variant of recombinant trypsin with increased substrate specificity for arginine versus lysine in non-animal host organisms. Moreover, the present invention relates to a variant of recombinant trypsin and their production. Also provided are use of recombinant porcine pancreatic trypsin variants for cleavage of precursors of insulins, and kits containing the variant of trypsin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102816785-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11518988-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102816785-A |
priorityDate |
2005-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |