| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84f5c6b72423de6f2f9c9c1a07572d3c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-4608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06G7-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate |
2004-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72939960096ee0baf2281aa13b4e5dc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a41e55857e3222922f97ac19a6bbbb1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b774ecf62ec71921af19d20a863aa5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e902d9d08d7e5ddeac1b5a680dded22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a22fe0cc8749875e6c737419aa8a9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efe87b5f4690692192ed67a66be0a397 |
| publicationDate |
2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7964534-B2 |
| titleOfInvention |
Nuclear magnetic resonance assembly of chemical entities using advanced antenna probes |
| abstract |
The invention provides a method for identifying a ligand that binds to a macromolecular target. The methods involve (a) attaching an antenna moiety to a first ligand, wherein the ligand binds specifically to a macromolecular target; (b) providing a sample comprising the macromolecular target, the first ligand and a candidate second ligand under conditions wherein the first ligand and the macromolecular target form a bound complex; (c) detecting a subset of magnetization transfer signals between the antenna moiety of the first ligand and the second candidate ligand, wherein the signals are obtained from an isotope edited NOESY spectrum of the sample; thereby determining that the two ligands are proximal in a bound complex, and identifying a second ligand that binds to the macromolecular target. |
| priorityDate |
2003-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |