http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7653490-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84f5c6b72423de6f2f9c9c1a07572d3c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08 |
filingDate | 2002-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b774ecf62ec71921af19d20a863aa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_257b6c39d9f74fe3c8084222d22e5a2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0248097b41ae2e56c7c6d15532d93b45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efe87b5f4690692192ed67a66be0a397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72939960096ee0baf2281aa13b4e5dc2 |
publicationDate | 2010-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7653490-B2 |
titleOfInvention | Nuclear magnetic resonance assembly of chemical entities |
abstract | The invention provides a method for obtaining a binding compound for a protein family, wherein the members of the protein family bind a common ligand. The method includes the steps of (a) providing a sample containing a protein from the protein family, a first ligand and a second ligand under conditions wherein the first ligand, the second ligand and the protein form a bound complex; (b) detecting magnetization transfer between the first ligand and the second ligand in the bound complex, thereby determining that the two ligands are proximal in the bound complex; and (c) obtaining a candidate binding compound including the first ligand, or a fragment thereof linked to the second ligand, or a homolog thereof, whereby the population contains binding compounds that bind to members of the protein family. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7964534-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011118148-A1 |
priorityDate | 2001-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 500.