| abstract |
Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: n n n n n n n n n n n n wherein n R is a C 2-10 alkenyl, a C 2-10 alkyl with an epoxy group or a C 5 -C 7 cycloalkyl with an epoxy group; n R 2 , R 3 and R 4 are each independently selected from the group consisting of hydrogen, C 1-4 alkyl, C 1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; n A is —OH or —NHR 5 , wherein R 5 is hydrogen or a C 1-3 alkyl; and n B is —R 1 -A or —R 6 , wherein R 1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R 6 is selected from the group consisting of C 1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and n m and n are integers with an m:n ratio from 30:1 to 3:1. |