| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77d9bf55e6700374867763cc2c6acaff |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
| filingDate |
2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b576850b45affb153f31be7a53a60033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_789cc742d6d8b424c280df27f845f395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6ad87617dd34de3420c550d8da76ba8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_715aa60f5dfb04d73889940478c0b252 |
| publicationDate |
2010-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7776565-B2 |
| titleOfInvention |
Engineering intracellular sialylation pathways |
| abstract |
Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846373-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9816107-B2 |
| priorityDate |
1999-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |