Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R27-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
filingDate |
2008-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cfb302fecc3515930c35e7d269add50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e776378e2e28550477305cc1138a64e |
publicationDate |
2010-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7754440-B2 |
titleOfInvention |
High-throughput screen for identifying selective persistent sodium channels channel blockers |
abstract |
A method for identifying a selective persistent Na + channel blocker by measuring the ability of the blocker to reduce or inhibit a persistent Na + current to a greater degree than a transient Na + current. Aspects of the present method provide Na + depletion/repletion methods for identifying a selective blocker of a persistent Na + channel, hyperpolarization methods for identifying a blocker of a persistent Na + channel, and Na/K ATPase pump inhibitor methods for identifying a selective blocker of a persistent Na + channel. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8871996-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013101926-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486647-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9540332-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859780-B2 |
priorityDate |
2001-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |