abstract |
The invention concerns a compound of the Formula (I) wherein m is 1-2 and each R 1 is a group such as cyano, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy; R 2 is trifluoromethyl or (1-6C)alkyl; R 3 is hydrogen or halogeno; and R 4 is isoxazolyl; or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines. |