| abstract |
A compound of formula (I): n nor a salt, or chemically protected form thereof, wherein: R 5 is an optionally substituted phenyl;n A is n n n n n n n n n n n n wherein Q is N; R 3 is selected from H, F, Cl and optionally substituted C 1-4 alkyl, C 1-4 alkoxy, C 5-7 aryl, and C 5-7 aryl-C 1-4 alkyl groups; R 4 is selected from H, F, Cl and optionally substituted C 1-4 alkyl, C 1-4 alkoxy, C 5-7 aryl, and C 5-7 aryl-C 1-4 alkyl groups; R 6 is selected from H, F, Cl, and optionally substituted C 1-4 alkyl, C 1-4 alkoxy, C 5-7 aryl, and C 5-7 aryl-C 1-4 alkyl groups; n D is selected from: n n n n n n n n n n n n n n n n B is selected from the group consisting of: n n n n n nWhere R N′ is selected from H and C 1-4 alkyl; where one of R P3 and R P4 is —C m -alkylene-R 2 and the other of R P3 and R P4 is H, m and n can be 0 or 1, and m+n=1 or 2; and additionally, when R P3 is —C m -alkylene-R 2 , m can also be 2 or 3, and m+n=1, 2, 3 or 4, and when R 2 is tetrazol-5-yl, m+n may be 0; or where one of R P3 and R P4 is —O—CH 2 —R 2 , and the other of R P3 and R P4 is H, n is 0; R N is H or optionally substituted C 1-4 alkyl; R 2 is either: (i) —CO 2 H; (ii) —CONH 2 ; (iii) —CH 2 —OH; or (iv) tetrazol-5-yl. |