| abstract |
Compositions designed to achieve constant butaprost concentrations of less than 1 mu M at the myometrium surface inhibit uterine contractions while avoiding undesired side-effects and are useful in preventing preterm labour. The compositions are in the form of infusions, pessaries, gels or tablets and may further include anti-microbials, e.g. metronidazole or cefuroxime and/or inhibitors of bacterial prostaglandins, e.g. nabumetone, flosulide and SC 58125. |