| abstract |
Complex comprising a peptide carrier of SEQ ID NO:1 GALFLGFLGAAGSTMGAWSQPKR 1 KRKVR 2 and an appropriate siRNA, wherein R 1 represents any amino acid residue and more preferably K or S, R 2 is null or represents one of the following groups: cysteamide, cysteine, thiol, amide, linear or ramified C 1 -C 6 alkyl optionally substituted, primary or secondary amine, osidic derivative, lipid, phospholipid or cholesterol and said siRNA is selected to silence a target mRNA. |