| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45c0430dd45ca6c64640c228acd8a48c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2006-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b05daeeb49af87bea5d4509eee669224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94e22af62d1684b19662c85b2d5011e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d6b15781519ccdfccfd0016cedf764
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff3f3ec9542f1243ed0ef74ce8243203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0f897c9cfe5b29e0ffa2ee3cdaace8a |
| publicationDate |
2008-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7378244-B2 |
| titleOfInvention |
Telomerase promoters sequences for screening telomerase modulators |
| abstract |
Telomerase reverse transcriptase is part of the telomerase complex responsible for maintaining telomere length and increasing the replicative capacity of progenitor cells. Telomerase activity is turned off in mature differentiated cells, but is turned back on again in hyperplastic diseases, including many cancers. This disclosure provides regulatory elements that promote transcription in cells that express telomerase reverse transcriptase (TERT). The disclosure also provides systems using TERT promoter sequences for identifying compounds that can be used to modulate telomerase expression. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006275267-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7517971-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7622549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8796438-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8709995-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004242529-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006040307-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009269739-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8222392-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7879609-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220438-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8236774-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008279871-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7585622-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7560437-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003096344-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7750121-B2 |
| priorityDate |
1997-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |