| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47c757b23cbbb06df098716ddf81eb48 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-04 |
| filingDate |
2002-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d55494c7fba4fb99f3099c1d3f76211
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3e3fde193d672994bd07c1650ade74c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4917dcc15176476cd65fc8d854826623 |
| publicationDate |
2007-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7157253-B2 |
| titleOfInvention |
Method for the production of (r)- and (S)-8-chloro-6-hydroxyoctanic acid alkyl esters by enzymatic reduction |
| abstract |
The invention relates to a method for the production of (R)- or (S)-8-chloro-6-hydroxyoctanoic acid alkyl esters of the general formula (R)-II or (S)-II n nin which R has the meaning C 1-4 -alkyl, from 8-chloro-6-oxooctanoic acid alkyl esters of the general formula In n nin which R has the above meaning, by enzymatic reduction using alcohol dehydrogenases, such as Lactobacillus brevis or Thermoanaerobium brokii , in the presence of cofactor regeneration systems.n n The resulting (R)- and (S)-8-chloro-6-hydroxyoctanoic acid esters can be converted in a known manner into (R)-α-lipoic acid and (S)-α-lipoic acid, respectively. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102012017026-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014032777-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294479-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106083811-B |
| priorityDate |
2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |