| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9259cfa966fe620251340a003f5d6125 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b68484113ad1845aa7031ddff0da43c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aec82285553ea7af2944ff63607bb50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a887bacbf7086e477b7921e0ff73e20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13fa817cd3184c4d284108c7418e19e7 |
| publicationDate |
2006-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7153491-B2 |
| titleOfInvention |
Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging |
| abstract |
This invention relates to a novel method of screening for inhibitors of beta-amyloid production, and thereby identifying such inhibitors as therapeutics for neurological and other disorders involving APP processing and beta-amyloid production. This invention also relates to identifying macromolecules involved in APP processing and beta-amyloid production. Furthermore, inhibitors identified by the screening method of the present invention are useful in the treatment of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273014-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8629136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273075-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249157-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9242941-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9242940-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8999918-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8414893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7906625-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9187434-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9133126-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9133139-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8822454-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9427442-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008292639-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9492469-B2 |
| priorityDate |
1998-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |