| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d08d60f05a67f5de3ec62deb54b6ef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-525 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 |
| filingDate |
2003-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365391758c2961851676455163031464
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00dd610b466243bc922a0b545c766435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c362ef91d3a64fe63c86966e6611882
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bc7fe4871c790a5d186a49645f4e3f4 |
| publicationDate |
2006-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7101978-B2 |
| titleOfInvention |
TNF-α binding molecules |
| abstract |
The present invention relates to TNF-α binding molecules and nucleic acid sequences encoding TNF-α binding molecules. In particular, the present invention relates to TNF-α binding molecules with a high binding affinity, a high association rate, a low dissociation rate with regard to human TNF-α and that are capable of neutralizing TNF-α at low concentrations. Preferably, the TNF-α binding molecules of the present invention comprise light and/or heavy chain variable regions with fully human frameworks (e.g. human germline frameworks). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015070009-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009012266-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005042680-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010080794-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010297103-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010085590-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2531547-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012323158-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790871-B2 |
| priorityDate |
2003-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |