Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K4-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 |
filingDate |
1998-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5853755799e977128cadf5627d113a0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_544b04e8180f2112e5311dc27b7ad93d |
publicationDate |
2006-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7030227-B1 |
titleOfInvention |
Cell regulatory genes, encoded products, and uses related thereto |
abstract |
This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005265434-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7773663-B2 |
priorityDate |
1997-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |